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Directions by compass point
From West: Greensboro, etc.
- Via 1-85 North: Exit onto N.C. 147 (Durham Freeway)
- Take first exit off Durham Freeway onto 15-501 S. toward Chapel Hill
- Stay in right lane, and take second exit (#107) to N.C. 751.
- Turn LEFT onto N.C. 751 S., go under the highway, and take next left turn onto Erwin Road.
- At third traffic light, take right onto Research Drive.
From North: Richmond, etc.
- Via I-85 South: In Durham, take the left-lane exit (#174B) for US 15-501 S. Bypass - Duke University/Chapel Hill.
- Continue on U.S. 15-501 to the fourth exit (#107) a right-lane exit for N.C. 751.
- Turn LEFT onto N.C. 751 S., go under the highway, and take next left turn onto Erwin Road.
- At third traffic light, take right onto Research Drive.
From East: Raleigh, etc.
- Via I-40 West: Exit onto the Durham Freeway (N.C. 147).
- Take Durham Freeway to Fulton Street exit (#15B).
- Turn left onto Fulton Street, take to end at Erwin Road.
- Turn right onto Erwin Road. At first traffic light, turn left onto Research Drive.
From South(west): Chapel Hill, etc.
- Via U.S. 15-501: North. Take 15-501 N. marked Duke Univ./Med Ctr. Do not take 15-501 Business.
- Take N.C. 751 exit (#107) marked Duke. Univ. West Campus.
- Turn right onto N.C. 751, make the next left turn onto Erwin Road.
- At third traffic light, take right onto Research Drive.