This is a section of the content taught by Jane and Dave Richardson for the BCH/SBB 681 - Physical Biochemistry - course at Duke University, Fall Semester 2012.

The information below will become a source of class materials - handouts, worksheets, and kinemage files. Downloads that are marked by a small blue downward pointing arrow:  download arrow    are handled so that a simple, single left click will lead to a successful download of the designated file with the correct name and correct format. (Unmarked downloads may need a right-click or other care to successfully download to where you prefer.) Many newer browsers are by default set so that "safe" files are opened upon download; as a practice this is not a good one; so turn that off for the rest of your scientific career.

Aug. 28, 2012

Models and structural informatics

Lecture Notes
 681LectureNotes20120828.doc (1MB)
Homework Assignment
download arrow bch681_Quick-start_for_KiNG.pdf (60KB)
download arrow bch681_WrkSht-H-bonds2012.pdf (160KB)
download arrow bch681_HbondPractice-KiNG.kin (105KB)
Aug. 30, 2012

Ramachandran Sterics And Distributions
Atomic Contacts And Molecular Motions


Lecture Notes
 681LectureNotes20120830.doc (1MB)
 XtalModel2DataEquation.pdf (1MB)
Homework Assignment
download arrow bch681_WrkSht2-motions.pdf (60KB)
download arrow bch681_c6FldFlx-KiNG_mod.kin (624KB)
download arrow bch681_Backrub_kinSup_mod.kin (624KB)

diffraction

Nov. 27, 2012

Allostery: Hemoglobin

Lecture Notes
 HB4-equil_20121126.pdf (210KB)
Homework Assignment
 HbAllo-KiNGques.kin (125KB)
 Wrksht-Hemoglobin-Questions.pdf (40KB)
 Perutz-1970-both.pdf (1.3MB)

(Unmarked downloads may need a right-click or other care to successfully download to where you prefer.)
Nov. 29, 2012

Mobility, Conformational Change, Ensembles, and Uncertainty/Error

Lecture Notes
 681LectureNotes20121129.doc (1MB)
Homework Assignment
download arrow bch681_WrkSht-Validation.pdf (80KB)