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This is the OLD home page for the ALWAYS CHANGING course - Structure of Biological Macromolecules - taught by Dave and Jane Richardson.

The table below will become a source of class materials - handouts, worksheets, and kinemage files. Two "flavors" of hyperlinks can be found in these two columns. The Subject column will contain links to other pages for display (or printing). The downloads column will contain links to files - typically kinemages - which you should download for use on your computer.

Depending on your browser's setup, certain files may be displayed rather than downloaded. In this case, you'll need to force the download by either "right-clicking" or control-clicking the link.

Subject ../downloads
click to download  ()=optional
1) Macromolecular Structure &
Interactive Computer Graphics
General Information
Using KiNG
Intro Lesson: Getting Comfortable with Protein Geometry
HTML ||  download arrow 222introWrksht.pdf (72KB)
files for intro graphics assignment:
2) H-bonds & Helices: Kinemages for these two lessons:
3) Beta Proteins: (α/β)8 & Greek Key Kinemages for this lesson: files for this lesson:
4) All-atom Contact Analysis: Files for this lesson:
5) The Ribosome: Files for this lesson:
6) Crystallographic Model Building: Files for this lesson:
7) Resources for projects: Files for this section:
  • download arrow VTF_noFlip100104_nDate_filtProt.txt.gz (file-level data) (1.2MB)
  • download arrow SS_nosym_232_T5200.kin.gz (3D disulfide kin) (1.1MB)
  • download arrow rota4400-SS_inChain.csv (multi-D disulfide spreadsheet) (264KB)
  • download arrow rota4400-Asn_all_psipsichi.kin.gz (3.2MB)
  • download arrow 2AAIed.pdb (kin tutorial example file) (389KB)
Ramachandran-Plot Data Analysis:
  • assignment & worksheet:  HTML || download arrow 222RamaPlotDataWrksht.pdf (68KB)
  • reading:   2003LovellProteins50.pdf
Files for this lesson:
  • download arrow rama4400-bch222-2011_short.csv.zip (5.1MB)
  • download arrow prepro-noGP_Blt30_wh.kin.gz (632KB)
  • download arrow rama4400_short_aaSort.kin.gz (4.6MB)
  • download arrow general-noGPIVpreP_justContours_atZ90.kin (96KB)
Sidechain Rotamer Data Analysis:
  • assignment:  HTML || download arrow 222rotamerPlotWrksht.pdf (84KB)
  • reading:   2000LovellProteins40.pdf
Files for this lesson:
  • download arrow rota4400-gln_ptm.kin.gz (832KB)
  • download arrow 1n83FH_Gln321_ecl_chi2.kin.gz (110KB)
  • download arrow rota4400-leu_byB.kin.gz (1.2MB)
  • download arrow 1xwlFH-Leu473.kin.gz (184KB)
  • download arrow 1xwlFH.pdb (820KB)
  • download arrow rota4400-Pro_cis-trans.kin.gz (1MB)
  • download arrow 1dy5-cisTransPro.kin.gz (204KB)
  • download arrow rota4400-SerThrVal_3D.kin.gz (204KB)
Structures by NMR:
  • assignment & worksheet:  HTML || download arrow 222nmrWrksht.pdf (68KB)
Files for this lesson:
  • download arrow Xia.kin (148KB)
  • download arrow Hyberts.kin (120KB)
  • download arrow 5ptiPaPb.kin (36KB)
  • download arrow Tendami.kin (352KB)
Planar geometry, and the wwPDB Validation Task Force
  • Graphics assignment and questions re. VTF
  • preprint of VTF report
Files for this lesson:
  • download arrow 3Dlit_tetr_CO_KiNG.kin
alpha / beta Proteins:
  • assignment & worksheet:  HTML || download arrow abBarrelWrksht.pdf (62KB)
Kinemages for this lesson:
  • download arrow babarel.kin (52KB)
  • download arrow abBarrel.kin (60KB)
  • download arrow 1tim_a.kin (96KB)
Greek Key β Barrels:
  • assignment & worksheet:  HTML || download arrow 222greekKeysWrksht.pdf (76KB)
Kinemages for this lesson:
  • download arrow StSurvey.kin (412KB)
  • download arrow 1E43gk.kin (48KB)
  • download arrow (c16Virus.kin) (352KB)