BCH 258
Structural Biochemistry I

This course introduces students to the principles of modern structural biology. The objective is to convey the importance of understanding fundamental biological processes in terms of the atomic properties of the macromolecules that participate in them. In this course we identify reoccurring structural principles and motifs and show how proteins with unrelated functions are built up from combinations of these. We then introduce methods of structure determination by X-ray crystallography and NMR. Finally, we use specific examples from the current literature to illustrate general structural principles.

Immediately below are PDFs with general information about the course. Following the general info is the tentative class schedule in columnar format. Listed with the date and topic are downloadable resources - PDFs, kinemages, and text files. The topics and/or resources may change during the course of the course. An assigned worksheet is generally expected to be done between the day it is listed and the following class. After the class schedule are links to additional resources on using kinemages and KiNG, both for class exercises and for projects.

Be attentive with your downloads! Kinemage files are text files and may display in the browser. If necessary, use some type of "right-click"; option-click; shift-right elbow-click combo to download the file or link. This may be true for some browsers even with PDF files.

• Course summary  258CourseSummary.pdf (76KB)
• General Info  258GenInfo20080825.pdf (84KB)
• Class Schedule 258ClassSchedule20080825.pdf (112KB)