RNA Backbone Conformers

This table contains links which will lead to display of a representative example of a conformer in an interactive KiNG display window. Below is essentially Table 1 - Characteristics of the 46 consensus clusters of RNA backbone suite conformation - from the RNA Ontology Consortium paper, "RNA backbone: Consensus all-angle conformers and modular string nomenclature" doi/10.1261/rna.657708. We may periodically update the statistics and representatives on this table.

To view and interact with the structural model for a chosen example, click the "KiNG" button in the column labeled "example". Drag with the left mouse button to rotate in 3D, and click on a point to identify it. Buttons in the righthand panel can turn on all-atom contacts (both H-bonds & vdW) for the suite, and either full structure for the local neighborhood or pseudo-backbone for a larger context. Suitable views are on the "Views" pulldown menu.


δ,δ,γ name comment example suite δ-1 ε-1 ζ-1 α β γ δ
33p 1a A-form Launch KiNG  ur0020 11 3'emmtp3' 81 -148 -71 -65 174 54 81
1m -β shoulder on 1a;
some intercalate
Launch KiNG rr0082 1940 3'emm-135p3' 84 -142 -68 -68 -138 58 86
1L +β shoulder on 1a;
some intercalate
Launch KiNG  rr0082 1460   86 -115 -92 -56 138 62 79
&a εζ shoulder on 1a;
weak Hb O2'(-1)-O4'
Launch KiNG  pr0037 B163   82 -169 -95 -64 -178 51 82
7a stack switch Launch KiNG  ar0041 A6 3'e-140mtp3' 83 -143 -138 -57 161 49 82
3a bases far 7a,3a,9a all touch in ζ Launch KiNG  urb016 A2 3'etmtp3' 85 -144 173 -71 164 46 85
9a bases far;
starts or ends loops
Launch KiNG  rr0082_2582   83 -150 121 -71 157 49 81
1g GNRA1-2; U-turn Launch KiNG  rr0082 1864 3'emttp3' 81 -141 -69 167 160 51 85
7d bases far; can span 2 helices Launch KiNG  rr0082 0636 3'emptp3' 84 -121 -103 70 170 53 85
3d bases far; starts or ends A-helix Launch KiNG  rr0082 2118 3'e-140ptp3' 85 -116 -156 66 -179 55 86
5d P(-1) to P(+1) close;
end or end+1 A-helix
Launch KiNG  ur0020 A9 3'epptp3' 80 -158 63 68 143 50 83
33t 1e S-motif strand2 "dent";
Hb O2'(-1)-O4'; low β
Launch KiNG  ur0035 A2665 3'em-110 80tp3' 81 -159 -79 -111 83 168 86
1c GNRA 4-5; ttt "crankshaft" version of 1a Launch KiNG  ur0020 A28 3'emttt3' 80 -163 -69 153 -166 179 84
1f +β shoulder on 1c;
stack switch or ∼intercalate
Launch KiNG  tr0001 A22 3'emt135t3' 81 -157 -66 172 139 176 84
5j bases far; 1-bulge return Launch KiNG  ar0027 B17 3'epp110t3' 87 -136 80 67 109 176 84
32p 1b leads into 2' suites;
k-turn O'; syn G Hb N2-OP2
Launch KiNG  pr0113 D208 3'emmtp2' 84 -145 -71 -60 177 58 145
1[ best intercalation conformation Launch KiNG  pr0019 B658 3'emm-135p2' 83 -140 -71 -63 -138 54 144
3b bases far; ends A-helix Launch KiNG  rr0082 0904 3'etmtp2' 85 -134 168 -67 178 49 148
1z UNCG 1-2; bulges Launch KiNG  rr0082 01771 3'emttp2' 83 -154 -82 -164 162 51 145
5z S-motif 1-2; Z32a dna;
Hb OP2(-1)-O2'
Launch KiNG  ur0026 A2654 3'epttp2' 83 -154 53 164 148 50 148
7p bases far Launch KiNG  pr0033 B8 3'e-140ptp2' 84 -123 -140 68 -160 54 146
32t 1t ttt version of 1b Launch KiNG  pte003 B907 3'emttt2' 81 -161 -71 180 -165 178 147
5q bases far Launch KiNG  pte003 B973 3'epp110t2' 82 -155 69 63 115 176 146
32m 1o Starts 1-bulge; wide in β Launch KiNG  rr0082_01108 3'emmtm2' 84 -143 -73 -63 -135 -66 151
7r k-turn 1-2 Launch KiNG  rr0082 0262 3'e-140ptm2' 85 -127 -112 63 -178 -64 150
23p 2a leads out of 2' suites;
1-bulge return
Launch KiNG  rr0082 01711 2'emmtp3' 145 -100 -71 -72 -167 53 84
4a bases far Launch KiNG  rr0082 02485 2'etmtp3' 146 -100 170 -62 170 51 84
0a cross-stacked A-helix Launch KiNG  rr0082 0265   149 -137 139 -75 158 48 84
#a i-1 to i base pair;
S-motif 3-4; low ε
Launch KiNG  rr0082 01371 2'etmtp3' 148 -168 146 -71 151 42 85
4g i-1 to i base pair; non S-motif Launch KiNG  ur0012 A226 2'etttp3' 148 -103 165 -155 165 49 83
6g sheared stack Launch KiNG  pr0122 R151 2'epttp3' 145 -97 80 -156 -170 58 85
8d some with Hb O2'(-1)-OP2(+1) Launch KiNG  rr0009 C1062 2'emptp3' 149 -89 -119 62 176 54 87
4d tRNA 58-9; Hb O2'(-1)-OP2(+1) Launch KiNG  tr0001_A59 2'etptp3' 150 -110 -172 80 -162 61 89
6d starts A-helix Launch KiNG  rr0082 0116 2'epptp3' 147 -119 89 59 161 52 83
23t 2h bases far Launch KiNG  rr0082 02540 2'emmtt3' 148 -99 -70 -64 177 176 87
4n ∼stack or sheared stack Launch KiNG  rr0082 0767   149 -85 100 81 -112 -178 83
0i -β next to 6n; bases perpendicular Launch KiNG  rr0082 0940   149 -85 100 81 -112 -178 83
6n UNCG 3-4; Z23 dna;
syn curled to base triple
Launch KiNG  rr0082 01773 2'epptt3' 150 -92 85 64 -169 177 86
6j -β next to 6n; bases far Launch KiNG  pte003 B975   142 -116 66 72 122 -178 84
22p 2[ UNCG 2-3; near B dna;
k-turn 3-4
Launch KiNG  rr0082 0264 2'emm-135p2' 146 -101 -69 -68 -150 54 148
4b Cross-stacked A-helix end Launch KiNG  rr0082 0247 2'etmtp2' 145 -115 163 -66 172 46 146
0b varied Launch KiNG  rr0082 0453 2'epmtp2' 148 -112 112 -85 165 57 146
4p often starts 1-bulge,
Hb O2'(-1)-N7(+1)
Launch KiNG  rr0096 A873 2'etptp2' 150 -100 -146 72 -152 57 148
6p k-turn 2-3 Launch KiNG  rr0082 01315 2'epptp2' 146 -102 90 68 173 56 148
22t 4s S-motif 2-3; low β Launch KiNG  ur0026 A2655   150 -112 170 -82 84 176 148
22m 2o bases perpendicular,
something between
Launch KiNG  pr0033 5 2'emmtm2' 147 -104 -64 -73 -165 -66 150