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The Anatomy and Taxonomy of Protein Structure

Jane S. Richardson¹

Department of Anatomy [now Department of Biochemistry]
Duke University, Durham, North Carolina²

Protein Anatomy . .

1. Background . .
   1. Introduction . .
   2. Amino Acids and Backbone Conformation . .
   3. Levels of Error . .
2. Basic Elements of Protein Structure . .
   1. Helices . .
   2. β Structure . .
   3. Tight Turns . .
   4. Bulges . .
   5. Disulfides . .
   6. Other Nonrepetitive Structure . .
   7. Disordered Structure . .
   8. Water . .
   9. Subunits and Domains . .

Protein Taxonomy . .

3. Classification of Proteins by Patterns of Tertiary Structure . .
   1. Summary of the Classification System . .
      1. Principles and Methods . .
      2. Outline of the Taxonomy . .
      3. Schematic Drawings of the Protein Domains by Structure Type . .
      4. Index of Proteins . .
   2. Antiparallel α Domains . .
   3. Parallel α/β Domains . .
   4. Antiparallel β Domains . .
   5. Small Disulfide-Rich or Metal-Rich Domains . .
4. Discussion . .
   1. Implications for Noncrystallographic Determination of Protein Structure . .
   2. Implications for Protein Evolution . .
   3. Implications for Protein Folding . .

Acknowledgments . .

References . .

[ Index ] . .